A Quick Overview of the Endocannabinoid System

The human body is full of mystery. It is so complex and intricate but all these finer details work perfectly and allow the human body to work as a unified whole. Normal and healthy adults can do just about anything but you may experience some discomfort or problems when your health falters like when you are sick. You may see visible signs and the person can voice out what symptoms they have but it is impossible to see just what exactly is going on inside your body. Some more common processes we are more familiar with but there are less known processes that are just as vital and makes a big difference to your overall health and well-being you are probably still clueless of until today.

The way the human body works is a marvel to the naked eye. Many of these processes aren’t directly visible to us but we continue to live and breathe each day without fully knowing or understanding the human body. There are so many things involved but works so perfectly and effortlessly it can amaze you at times. Unfortunately, the human health is not always in great shape and it can break down and not work properly too when one is sick or not in the best of health. While it is unavoidable to get sick at times, you can prevent it if you know your body well and also if you do your part in taking good care of it. Stress can get the best of you sometimes but you’d be able to bounce back right away if your body is up for the job of defending your health whenever pathogens or sickness strike.

Curious about Cannabis

Medical cannabis is gaining prominence in society for the past decade. It is no longer the marijuana that many used to frown on before because of the associated stigma to its use. It has completely turned a new leaf and reinvented itself. People no longer just see it as a recreational drug but as a substance with therapeutic value even if the FDA still has not given its approval yet. After all, many doctors already prescribe it to their patients especially the ones diagnosed with a chronic untreatable condition where only palliative treatment works. Just what makes CBD special then?

What is the Endocannabinoid System (ECS)?

What many of you do not know is that cannabis mimics the actions of the endocannabinoid system. The human body has special receptor cells that can bind to the active components found in cannabis. These interactions can produce beneficial properties that are good for one’s health and even relieve symptoms of some of the most painful and persistent ailments known to men like cancer, chronic pain, anxiety, and epilepsy among others. Now, how does the endocannabinoid system works? Similar to how lock and keys work, the endocannabinoid system is made up of receptors that act as locks and the agonists to these receptors serve as the keys. These agonists are tiny molecules of chemicals that can trigger various reactions in the body. What happens is that certain reactions are triggered when the receptor meets an agonist depending on what agonists and receptors are involved.

There are two receptor types involved in the endocannabinoid system. These are cannabinoid receptor 1 (CB1) and cannabinoid receptor 2 (CB2). Endocannabinoids are the agonists or keys of the CB1 and CB2 receptor. “Endo” means “within” while “cannabinoid” pertains to the compound that matches cannabinoid receptors. The two most prominent endocannabinoids in the human body are anandamide 2-Ag. The former was discovered because of THC’s help.

As a system, endocannabinoids are helpful in the regulation of certain body processes that involve other body organs like the brain, musculoskeletal and immune system, among others. Our body makes its own cannabinoids similar to cannabis’ CBD and THC that helps maintain that sensitive balance so we don’t get sick or succumb to stress or anxiety because of the daily grind. The times our own ECS stops working properly that is when we experience discomforts and symptoms of certain infections or diseases. Remember that there are various body functions that are directly and indirectly regulated by the ECS such as the following:

• Appetite and food intake
• Digestion
• Fertility and reproduction
• Hunger
• Memory
• Mood
• Pain
• Sleep
• Regulate body temperature
• Pleasure and reward

Experts have noticed the important role the endocannabinoid system plays in not only promoting optimal health but in managing and treating a number of diseases and conditions even better than conventional medicine and treatment regimens. The ECS is helpful in the following conditions once its activities are well-modulated:

• Atherosclerosis
• Cancer
• Glaucoma
• Huntington’s
• Hypertension
• Multiple Sclerosis
• Myocardial Infarction
• Neuropathic pain
• Osteoporosis
• Spinal cord injury

The good thing about modern science is that we can now mimic and enhance the effects of the ECS without suffering from the addictive and psychoactive properties elicited by THC since there are plenty of CBD-rich cannabis sold in the market today. With your doctor’s prescription and the right dose computed for your specific condition, you’d be able to enjoy all the benefits offered by CBD to the human body without experiencing any unintended side effects. Hence, it is worth considering how helpful that we now have access to an external source of CBD agonists to trigger specific reactions/actions through CBD-rich medical cannabis.

And with the growing list of US states now legalizing marijuana farming, growth, and use, it is easier to have access to this once highly stigmatized plant and you may not even need to relocate anymore whether you intend to use cannabis for recreational or medical use. It’s also fun to take it since there are various choices to choose from ranging from the usual edibles to CBD oil that is all the rage now. We will likely learn more about the full potential of CBD since there are still plenty of studies and research being done to find out what else CBD is capable of doing aside from what we already know. Maybe by then, it will be able to get the seal of approval from the FDA, so it can finally be marketed as a therapeutic drug and an answer to the prayers of many people.